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The communication between protected applications and the CodeMeter Runtime Server is done using TCP/IP. The default port is 22350. You may need to allow communication on port 22350 for TCP and UDP if a firewall is running on your system. If your firewall filters the traffic using the application name you need to unblock CodeMeter.exe (%Programme%\CodeMeter\Runtime\bin). Please note that some antivirus programs also contain firewall functionality.